Biotin-Osimertinib  

Biotin-Osimertinib is a biotinylated derivative of osimertinib, a third-generation EGFR tyrosine kinase inhibitor (EGFR-TKI) used in cancer therapy. The biotin tag enables avidin/streptavidin binding, allowing osimertinib to be used in affinity assays, target identification, and drug delivery studies while retaining its kinase inhibitory functionality.
Applications:
Target engagement studies to identify osimertinib binding partners.
Affinity purification or pull-down assays using streptavidin systems.
Cellular uptake and biodistribution tracking of osimertinib derivatives.
Development of biotin-based drug delivery platforms.

msds of Biotin-Osimertinib